Viscous Behaviour and Interactive Nature of Indigenous Legume Seed Galactomannas and Biodegradable Nanoparticles for Drug Delivery

Background: Galactomannans are the seed polysaccharides also known as gums, mostly isolated from legume endosperm. can easily mix with xanthans by physical association, exhibits synergistic effect and form complex mixtures due to their entangle nature in deferent ratios. Polysaccharides having these properties make them versatile materials which useful different biomedical food applications additives, thickening, gelling agents, emulsifiers stiffeners. Biopolymer-based colloidal particles have potential application drug gene delivery. Methods: extracted indigenous endosperm Adenanthera pavonna L Mimosa pudica L. investigated during 2015-2021 for aspects i.e. viscous behaviour interaction properties, formation other polysaccharide like xanthan preparation characterisation of galactomannan-based nanoparticles obtained covalent cross-linking genipin. Result: The intrinsic viscosity A. M. measured compared commercial LBG (Locust Bean gum). Prepared small spherical shaped diameters ~33 67 nm negative zeta ~-9.2 - 19.0 mV were obtained. We suggest that crosslinking genipin on residual protein fraction both galactomannans. biodegradable offer be a new platform oral delivery nutraceuticals.